Biochemist – Synergy Bioscience

Synergy Bioscience, a leading contract research organization (CRO), provides cutting-edge product development support along with comprehensive analytical chemistry and microbiology testing services for the life sciences industry. We are seeking a motivated and experienced Senior Biochemist to join our dynamic team.

Position Overview:

The ideal candidate will possess extensive hands-on laboratory experience in areas such as biochemistry, enzymology, or chemical biology. A strong passion for both the theoretical and practical applications of biochemistry is essential. Success in this role requires not only scientific expertise but also a growth mindset, a proactive attitude, teamwork, and strong communication skills.

Key Responsibilities:

• Execute biochemical assays to support product development activities.
• Collect, analyze, and interpret scientific data, and present findings to clients with clarity and precision.
• Collaborate effectively with internal teams and external partners to drive projects toward their milestones.
• Troubleshoot and resolve scientific challenges in a timely and effective manner.
• Prepare technical reports in compliance with Good Documentation Practices (GDP).

Specialized Expertise:

• In-depth experience with IC50 and Kd determination, enzyme potency assays, protease and proteolytic hydrolysis, ligand-binding affinity measurements, and enzyme kinetics.
• Proficiency in techniques such as fluorescence, isothermal titration calorimetry (ITC), differential scanning calorimetry (DSC), protein purification, and potency assays for protease casein activity.

Chemical Testing and Sample Handling:

• Experience in dealing with chemical isolation from tissues, as well as homogenization of tissues (adipose, liver, kidney) using appropriate buffers.
• Mastery of solid-phase extraction (SPE) techniques for purifying certain chemicals from tissue extracts, including adipose, liver, and kidney tissues.
• Skilled in the determination of developing and validating assays using advanced analytical techniques such as HPLC, LC-MS/MS, and/or GC-MS.

Additional Skills and Qualifications:

• Expertise in molecular techniques such as Western blotting, PCR, and immunohistochemistry for the analysis of proteins and enzymes in biological samples.
• Familiarity with microscopy (light, fluorescence, and electron) and histology, including tissue staining, sectioning, and slide preparation.
• Strong skills in data analysis, including statistical methods and data interpretation, with the ability to compile and review comprehensive scientific reports.
• Hands-on experience with laboratory equipment, including centrifuges, spectrophotometers, automated analyzers, and liquid handling robots, with an ability to troubleshoot and maintain lab instruments.
• Deep understanding of regulations and testing standards, ensuring compliance with quality control and assurance protocols.

Education and Experience:

• Ph. D. in Biochemistry.
• A minimum of 5 years of solid industry experience, particularly in biochemistry Laboratory testing.

If you are ready to take on this exciting role and contribute to our innovative research and development efforts, please submit your resume. We will reach out to qualified candidates to discuss the next steps.